IMPORTANT SAFETY INFORMATIONClick here for a larger view

VANTAS is indicated in the palliative treatment of advanced prostate cancer.
Do not use VANTAS if you are allergic to the drug histrelin.
Prostate cancer-related symptoms may become worse during the first few weeks of treatment.

There may be pain and discomfort during and after VANTAS insertion and removal. Bruising and redness may occur. These reactions, if they occur, are usually mild and heal without treatment within 2 weeks. If they do not heal, contact your doctor.
In clinical trials, the most common side effects related to VANTAS were hot flashes, fatigue, skin reactions at the insertion site, testicular atrophy, and brief periods of reduced renal function.
Like other hormone suppression therapies, VANTAS may cause breast pain or impotence of varying duration in some patients.
There is a chance that your bones may become weakened (known as osteoporosis) if you use this type of drug for long periods of time. Ask your doctor if this is a risk for you.
This is not a complete list of all the possible side effects. If you need more information, or are worried about these or other side effects, talk to your doctor.